Pinewood Cold Sore Cream
- Revised
- June 2024
- Source updated
- 05 Mar 2026
- MA number
- PL 04917/0066
- Legal status
- General Sales List
Indications
Concepts (25)
+Allergy to the medicineContraindicated
Hypersensitivity to aciclovir, valaciclovir, propylene glycol to any of the excipients listed in section 6.1.
Source SmPC ↗+Propylene glycolContraindicated
Hypersensitivity to aciclovir, valaciclovir, propylene glycol to any of the excipients listed in section 6.1.
Source SmPC ↗+AlcoholWarning
d be encouraged to consult a physician concerning the treatment of an infection. Cold sore sufferers should be advised to avoid transmitting the virus, particularly when active lesions are present. The excipient propylene glycol can cause skin irritations and the excipient cetyl alcohol can cause local skin reactions (e.g. contact dermatitis)
Source SmPC ↗+Blood disordersWarning
branes such as inside the mouth or vagina, or on the eye. Particular care should be taken to avoid contact with the eye. Not for use for the treatment of genital herpes or ocular herpes infections. Not recommended for use by patients who know they are immunocompromised e.g. by HIV infection, bone marrow transplant or cancer treatment, except on the advice of a doctor. Such individuals should be encouraged to consult a physician concerning the treatment of an infection. Cold sore sufferers should be advised to avoid transmitting the virus, particularly when active lesions are present. The excipient propylene glycol can cause skin irritations and the excipient cety
Source SmPC ↗+InfectionWarning
should be encouraged to seek medical advice. Not to be applied to mucous membranes such as inside the mouth or vagina, or on the eye. Particular care should be taken to avoid contact with the eye. Not for use for the treatment of genital herpes or ocular herpes infections. Not recommended for use by patients who know they are immunocompromised e.g. by HIV infection, bone marrow transplant or cancer treatment, except on the advice of a doctor. Such individuals should b
Source SmPC ↗+CancerWarning
branes such as inside the mouth or vagina, or on the eye. Particular care should be taken to avoid contact with the eye. Not for use for the treatment of genital herpes or ocular herpes infections. Not recommended for use by patients who know they are immunocompromised e.g. by HIV infection, bone marrow transplant or cancer treatment, except on the advice of a doctor. Such individuals should be encouraged to consult a physician concerning the treatment of an infection. Cold sore sufferers should be advised to avoid transmitting the virus, particularly when active lesions are present. The excipient propylene glycol can cause skin irritations and the excipient cety
Source SmPC ↗+Eye conditionsWarning
should be encouraged to seek medical advice. Not to be applied to mucous membranes such as inside the mouth or vagina, or on the eye. Particular care should be taken to avoid contact with the eye. Not for use for the treatment of genital herpes or ocular herpes infections. Not recommended for use by patients who know they are immunocompromised e.g. by HIV infection, bone marrow transplant or cancer treatment, except on the advice of a doctor. Such individuals should b
Source SmPC ↗+UnclassifiedWarning
Only recommended for use on cold sores on the lips and face. People with particularly severe recurrent herpes labialis should be encouraged to seek medical advice. Not to be applied to mucous membranes such as inside the mouth or vagina, or on the eye. Parti
Source SmPC ↗+Kidney conditionsInteraction
Probenecid increases the mean half-life and area under the plasma concentration curve of systemically administered aciclovir. Other drugs affecting renal physiology could potentially influence the pharmacokinetics of aciclovir. However this is likely to be of little relevance to the cutaneous application of aciclovir. No interactions with other drugs have been described for topical Acyclovir.
Source SmPC ↗+BreastfeedingPregnancy
Pregnancy No specific studies of topical aciclovir have been carried out in pregnant women or nursing mothers. So far, no relevant plasma levels have been measured and no systemic effects have been observed. A post-marketing aciclovir pregnancy registry has documented pregnancy outcomes in women exposed to
Source SmPC ↗+FertilityPregnancy
m should be considered only when the potential benefit outweighs the possibility of unknown risks however the systemic exposure to aciclovir from topical application of aciclovir cream is very low. Fertility Largely reversible adverse effects on spermatogenesis in association with overall toxicity in rats and dogs have been reported only at doses greatly in excess of those employed therapeutically. Two
Source SmPC ↗+ChildrenPregnancy
vir tablets on human female fertility. Aciclovir tablets have been shown to have no definite effect upon sperm count, morphology or motility in man. See Clinical Studies in section 5.2. Lactation Following oral administration of 200 mg aciclovir five times a day, aciclovir has been detected in breast milk at concentrations ranging from 0.6 to 4.1 times the corresponding plasma levels. These levels would potentially expose breast fed infants to aciclovir doses of up to 0.3 mg/kg/day. The dosage received by a nursing infant following maternal use of aciclovir cream would be expected to be insignificant.
Source SmPC ↗+PregnancyPregnancy
Pregnancy No specific studies of topical aciclovir have been carried out in pregnant women or nursing mothers. So far, no relevant plasma levels have been measured and no systemic effects have been observed
Source SmPC ↗+Benzyl alcoholNot in scanned sections
+Taken with other medicinesNot in scanned sections
+DehydrationNot in scanned sections
+Older peopleNot in scanned sections
+Enzyme deficiencyNot in scanned sections
+Intolerance to an ingredientNot in scanned sections
+Liver conditionsNot in scanned sections
+LactoseNot in scanned sections
+Sodium and potassium contentNot in scanned sections
+Sugar alcoholsNot in scanned sections
+Breathing conditionsNot in scanned sections
+Gap needed after another medicineNot in scanned sections
Storage and shelf life
§6.3 — Shelf life
3 years (unopened)
6 weeks (open)
§6.4 — Special precautions for storage
Do not store above 25°C. Do not refrigerate.