… block in patients without a functioning pacemaker.
• Severe bradycardia (less than 50 beats per minute).
• Left ventricular failure with pulmonary stasis.
• Decompensated cardiac failure.
• Lactation.
• Concurrent use with dantrolene infusion (see section 4.5).
• Combination with ivabradine (see section 4.5).
• Concurrent use with lomitapide (see section 4.5).
• Concurrent use with asunapr …
Identical in all 3 labels. Surrounding text shown from Ethypharm UK Ltd.
… uld not be administered intravenous diltiazem. • Combination with ivabradine (see section 4.5) • Concurrent use with lomitapide (see section 4.5) • Concurrent use with asunaprevir (see section 4.5) • Lactation
Identical in both labels. Surrounding text shown from Zentiva.
… recipitate ventricular tachycardia.
Diltiazem is contraindicated in combination with ivabradine (see section 4.5)
Diltiazem should not be used in patients with known hypersensitivity to diltiazem.
Diltiazem should not be used during pregnancy, by women of child-bearing potential, or by women who are breastfeeding.
… antrolene infusion (see section 4.5). Diltiazem is also contraindicated in combination with ivabradine (see section 4.5). Diltiazem should not be used concurrently with lomitapide (see section 4.5).
Diltiazem is contraindicated in pregnancy, in women of childbearing potential not using effective contraception and while breast-feeding (see section 4.6).
… city in certain animal species (rat, mice, rabbit). Diltiazem is contraindicated during pregnancy (see section 4.3), as well as in women of child-bearing potential not using effective contraception.
Diltiazem is excreted in breast milk at low concentrations. Breast-feeding while taking this drug should be avoided. If use of diltiazem is considered medically essential, an alternative method of infant feeding should be instituted.
Identical in both labels. Surrounding text shown from Napp Pharmaceuticals Limited.
… nce of adequate evidence of safety in human pregnancy, dilitiazem is therefore not recommended during pregnancy as well as in women of child- bearing potential not using effective contraception.
Breast-feeding
Diltiazem hydrochloride is excreted in breast milk at low concentrations. One report suggests that concentrations in breast milk reach similar levels to those in serum. Breast-feeding while taking …