… of the excipients listed in section 6.1.
• Sick sinus syndrome, 2nd or 3rd degree AV block in patients without a functioning pacemaker.
• Severe bradycardia (less than 50 beats per minute).
• Left ventricular failure with pulmonary stasis.
• Decompensated cardiac failure.
• Lactation.
• Concurrent use with dantrolene infusion (see section 4.5).
• Combination with ivabradine (see section 4.5).
• Concurrent use with lomitapide …
Identical in all 3 labels. Surrounding text shown from Ethypharm UK Ltd.
… except in the presence of a functioning ventricular pacemaker. • Second- or third-degree AV block except in the presence of a functioning ventricular pacemaker. • Severe bradycardia (below 40 bpm) • Left ventricular failure with pulmonary congestion • Concomitant use of dantrolene infusion (see section 4.5). • Additionally, for the intravenous forms, patients known to have an accessory bypass (Wolf-Parkinson-White syndrome or short PR syndrome), …
Identical in all 3 labels. Surrounding text shown from Zentiva.
Pregnancy and in women of child bearing capacity.
Patients with severe bradycardia (less than 40 bpm), second or third degree heart block, sick sinus syndrome, decompensated cardiac failure, patients with left ventricular failure with pulmonary congestion.
Concurrent use with dantrolene infusion because of the risk of ventricular fibrillation (see section 4.5).
Hypersensitivity to diltiazem or to any of the excipients.
Concurrent use with lomitapi …
Identical in both labels. Surrounding text shown from Napp Pharmaceuticals Limited.
Diltiazem depresses atrioventricular node conduction and is therefore contraindicated in patients with severe bradycardia (less than 50 bpm), sick sinus syndrome, congestive heart failure, and left ventricular failure with second or third degree AV or sino-atrial block, except in the presence of a functioning pacemaker. Diltiazem is also contraindicated in left ventricular failure with pulmonary stasis as diltiazem may have mild negative effects on contractility.
Diltiazem is contraindicated in acute complicated myocardial infarction (e.g. bradycardia hypotension, congestive heart failure/reduced LV function), pulmonary congestion, hypotension (<90 mmHg syst …
Hypersensitivity to the active substance or to any of the excipients listed in section 6.1.
Diltiazem is contraindicated in patients with severe bradycardia (below 40 bpm); in sick sinus syndrome or in second- or third-degree AV block, in patients without a functioning pacemaker; in left ventricular failure with pulmonary congestion. Diltiazem should not be given concomitantly with dantrolene infusion (see section 4.5). Diltiazem is also contraindicated in combination with ivabradine (see section 4.5). Diltiazem should not be used concurrently with lomitapide (see section 4.5).
Diltiazem is contraindicated in pregnancy, in women of childbearing potential not using effective contraception and while breast-feeding (see section 4.6).