… ntestinal bleeding or perforation, related to previous NSAIDs therapy.
• Active or history of recurrent peptic ulcer/haemorrhage (two or more distinct episodes of proven ulceration or bleeding).
• Patients with phaeochromocytoma, closed angle glaucoma, diabetes or thyroid disease.
• Patients with history of haemorrhagic stroke.
• Patients suffering from heart disease, circulatory problems, prostatic hypertrophy, hypertension, coronary artery disease, angina pectoris, tachyca …