… should undergo regular medical supervision to monitor for adverse events.
Ibuprofen should only be administered under strict consideration of the benefit-risk ratio in the following conditions:
- Systemic Lupus Erythematosus (SLE) or mixed connective tissue diseases. - Congenital disturbance of porphyrin metabolism (e.g. acute intermittent porphyria) - The first and second trimester of pregnancy - Lactation
Special care has to be taken in the following cases: - Gastrointestinal diseases including chronic inflammatory intestinal disease (ulcerative colitis, Crohn's disease) - Cardiac insufficiency and …