Acea 0.75% w/w Gel

Concepts (30)

• +Allergy to the medicineContraindicated

  Known hypersensitivity to metronidazole, parabens or any of the constituents.

  Source SmPC ↗
• +Benzyl alcoholWarning

  … n the metabolite of metronidazole. The clinical significance of this is not known at present. However in patients undergoing haemodialysis, metronidazole and its metabolites are efficiently removed. Contains methyl parahydroxybenzoate (E218) and propyl parahydroxybenzoate (E216) and ethyl parahydroxybenzoate (E214), may cause allergic reactions (possibly delayed).

  Source SmPC ↗
• +Dialysis and blood filteringWarning

  Warnings: Avoid contact with the eyes. If contact with the eyes occurs the gel should be washed out carefully with water. Precautions: The following statements take into account the possibility that metronidazole may be absorbed after topical application. However there is no evidence of any significant systemic concentrations of metronidazole following topical applications. Peripheral neuropathy has been reported in association with prolonged use of oral metronidazole. The elimination half-life of metronidazole remains unchanged in the presence of renal failure. Such patients, however, retain the metabolite of metronidazole. The clinical significance of this is not known at present. However in patients undergoing haemodialysis, metronidazole and its metabolites are efficiently removed. Contains methyl parahydroxybenzoate (E218) and propyl parahydroxybenzoate (E216) and ethyl parahydroxybenzoate (E214), may cause allergic reactions (possibly delayed).

  Source SmPC ↗
• +Kidney conditionsWarning

  Warnings: Avoid contact with the eyes. If contact with the eyes occurs the gel should be washed out carefully with water. Precautions: The following statements take into account the possibility that metronidazole may be absorbed after topical application. However there is no evidence of any significant systemic concentrations of metronidazole following topical applications. Peripheral neuropathy has been reported in association with prolonged use of oral metronidazole. The elimination half-life of metronidazole remains unchanged in the presence of renal failure. Such patients, however, retain the metabolite of metronidazole. The clinical significance of this is not known at present. However in patients undergoing haemodialysis, metronidazole and its metabolites are efficiently removed. Contains methyl parahydroxybenzoate (E218) and propyl parahydroxybenzoate (E216) and ethyl parahydroxybenzoate (E214), may cause allergic reactions (possibly delayed).

  Source SmPC ↗
• +UnclassifiedWarning

  Warnings: Avoid contact with the eyes. If contact with the eyes occurs the gel should be washed out carefully with water. Precautions: The following statements take into account the possibility that metronidazole may be absorbed after topical application. However there is no evidence of any significant systemic concent …

  Source SmPC ↗
• +AlcoholInteraction

  Patients are advised not to take alcohol during systemic metronidazole therapy because of the possibility of a disulfiram-like reaction. Some potentiation of anti-coagulant therapy has been reported when metronidazole has been used with the warfarin type oral anticoagulants. Patients receiving phenobarbitone metabolise metronidazole …

  Source SmPC ↗
• +BreastfeedingPregnancy

  The safety of topically applied metronidazole in pregnancy and lactation has not been adequately established and should not be used in these circumstances unless the physician considers it essential.

  Source SmPC ↗
• +PregnancyPregnancy

  The safety of topically applied metronidazole in pregnancy and lactation has not been adequately established and should not be used in these circumstances unless the physician considers it essential.

  Source SmPC ↗
• +Bleeding risk—Not in scanned sections

  Not found in the sections read for this label. Not the same as the label being silent.

• +Taken with other medicines—Not in scanned sections

  Not found in the sections read for this label. Not the same as the label being silent.

• +Intolerance to an ingredient—Not in scanned sections

  Not found in the sections read for this label. Not the same as the label being silent.

• +Fertility—Not in scanned sections

  Not found in the sections read for this label. Not the same as the label being silent.

• +Stomach and gut—Not in scanned sections

  Not found in the sections read for this label. Not the same as the label being silent.

• +Blood disorders—Not in scanned sections

  Not found in the sections read for this label. Not the same as the label being silent.

• +Heart rhythm block—Not in scanned sections

  Not found in the sections read for this label. Not the same as the label being silent.

• +Liver conditions—Not in scanned sections

  Not found in the sections read for this label. Not the same as the label being silent.

• +Low blood pressure—Not in scanned sections

  Not found in the sections read for this label. Not the same as the label being silent.

• +Infection—Not in scanned sections

  Not found in the sections read for this label. Not the same as the label being silent.

• +Lactose—Not in scanned sections

  Not found in the sections read for this label. Not the same as the label being silent.

• +Cancer—Not in scanned sections

  Not found in the sections read for this label. Not the same as the label being silent.

• +Sodium and potassium content—Not in scanned sections

  Not found in the sections read for this label. Not the same as the label being silent.

• +Blockage—Not in scanned sections

  Not found in the sections read for this label. Not the same as the label being silent.

• +Children—Not in scanned sections

  Not found in the sections read for this label. Not the same as the label being silent.

• +Sugar alcohols—Not in scanned sections

  Not found in the sections read for this label. Not the same as the label being silent.

• +Porphyria—Not in scanned sections

  Not found in the sections read for this label. Not the same as the label being silent.

• +Propylene glycol—Not in scanned sections

  Not found in the sections read for this label. Not the same as the label being silent.

• +Heart rhythm (QT interval)—Not in scanned sections

  Not found in the sections read for this label. Not the same as the label being silent.

• +Shock—Not in scanned sections

  Not found in the sections read for this label. Not the same as the label being silent.

• +Blood vessel conditions—Not in scanned sections

  Not found in the sections read for this label. Not the same as the label being silent.

• +Wheat starch—Not in scanned sections

  Not found in the sections read for this label. Not the same as the label being silent.