… ertain.
Caution should however be exercised by balancing the potential benefits of treatment against any possible hazard. Findings from reproduction toxicology studies are included in Section 5.3.
Breast-feeding:
Following oral administration of 200 mg aciclovir five times a day, aciclovir has been detected in breast milk at concentrations ranging from 0.6 to 4.1 times the corresponding plasma levels. These …
Identical in all 3 labels. Surrounding text shown from Aurobindo Pharma - Milpharm Ltd..
… rtain.
Caution should however be exercised by balancing the potential benefits of treatment against any possible hazard. Findings from reproduction toxicology studies are included in Section 5.3.
Breastfeeding
Following oral administration of 200 mg Aciclovir five times a day, aciclovir has been detected in breast milk at concentrations ranging from 0.6 to 4.1 times the corresponding plasma levels. These …
… ain.
Caution should therefore be exercised by balancing the potential benefits of treatment against any possible hazard. Findings from reproduction toxicology studies are included in Section 5.3.
Lactation
Following oral administration of 200mg aciclovir five times a day, aciclovir has been detected in breast milk at concentrations ranging from 0.6 to 4.1 times the corresponding plasma levels. These …
… xicity. Animal studies do not indicate reproductive toxicity (see section 5.3).
The use of Aciclovir 25mg/ml Concentrate for Solution for Infusion may be considered during pregnancy, if necessary.
Breast-feeding
Aciclovir is excreted in human milk, caution is therefore advised if aciclovir is to be administered to a nursing woman. It is unlikely that therapeutic doses of aciclovir have effects on the breas …
Pregnancy
No specific studies of topical aciclovir have been carried out in pregnant women or nursing mothers.
So far, no relevant plasma levels have been measured and no systemic effects have been observed.
A post-marketing aciclovir pregnancy registry has documented pregnancy outcomes in women exposed to …
… standard test in rats, foetal abnormalities were observed but only following such high subcutaneous doses that maternal toxicity was produced. The clinical relevance of these findings is uncertain.
Lactation:
As there is only minimal systemic absorption of aciclovir, adverse effects on the infant during lactation are unlikely. Limited human data show that the drug does pass into breast milk following sy …