… uation of therapy.
Patients should be advised not to take alcohol during Metronidazole therapy and at least 48 hours afterwards because of a disulfram-like effect (flushing, vomiting, tachycardia).
In the case of severe hypersensitivity reactions (e.g. anaphylactic shock), treatment with Metronidazole 500 mg/100 ml Solution for Infusion must be discontinued immediately and established emergency treatment must be initiated by qualified healthcare professionals.
Severe persistent diarrhoea occurring during treatment or during the subsequent weeks may be due to pseudomembranous colitis (in most cases caused by Clostridioides difficile), see section 4.8. This …
… ported in patients treated with metronidazole. The appearance of abnormal neurological signs demands the prompt evaluation of the benefit/risk ratio of the continuation of therapy (see section 4.8).
In the case of severe hypersensitivity reactions (e.g. anaphylactic shock; see also section 4.8), treatment with Metronidazole must be discontinued immediately and established emergency treatment must be initiated by qualified healthcare professionals.
Severe persistent diarrhoea occurring during treatment or during the subsequent weeks may be due to pseudomembranous colitis (in most cases caused by Clostridium difficile), see section 4.8. This in …