… upper gastrointestinal bleeding or perforation, related to previous NSAID therapy.
- History of hemophilia, hypothrombinemia or other clotting disorders
- Renal failure (GFR < 15mL/min/1.73m2).
- Hepatic failure.
- Third trimester of pregnancy
children under 16 years and when breast feeding because of possible risk of Reyes Syndrome.
Identical in both labels. Surrounding text shown from Haleon UK Trading Limited.
… ther kinds of bleeding such as cerebrovascular haemorrhages.
• Haemorrhagic diathesis; coagulation disorders such as haemophilia and thrombocytopenia.
• Patients who are suffering from gout.
• Severe hepatic impairment.
• Severe renal impairment.
• Doses >100 mg/day during the third trimester of pregnancy (see section 4.6);
• Methotrexate used at doses >15mg/week (see section 4.5).
Identical in both labels. Surrounding text shown from Dexcel Pharma Ltd.
… episodes of proven ulceration or bleeding, or other kinds of bleeding such as cerebrovascular haemorrhages; - Haemorrhagic diathesis; coagulation disorders such as haemophilia and thrombocytopenia; - Severe hepatic impairment; - Severe renal impairment; - Severe cardiac insufficiency; - Doses >100 mg/day during the third trimester of pregnancy (see section 4.6); - Methotrexate used at doses >15 mg/week (see section 4.5).
… ration or dyspepsia.
• Haemophilia or other haemorrhagic disorder (including thrombocytopenia) as there is an increased risk of bleeding.
• Concurrent anticoagulant therapy should be avoided.
• Severe hepatic impairment
• Severe renal impairment
• Severe cardiac failure
• Third trimester of pregnancy
• Methotrexate used at doses >15mg/week (see section 4.5).
• Children under 16 years old, unless specifical …
There is a possible association between aspirin and Reye's syndrome when given to children. Reye's syndrome is a very rare disease, which affects the brain and liver, and can be fatal. For this reason, aspirin should not be given to children aged under 16 years unless specifically indicated (e.g. for Kawasaki's disease).
Aspirin can reduce uric acid excretions and therefore should be used with care in patients with gout or a history of gout.
Before commencing long-term aspirin therapy for the management of cerebrov …