… n. Temporary discontinuation of treatment may be necessary.
• Systemic lupus erythematosus and other connective tissue disorders (hepatic and renal function may be impaired in these conditions)
• Thyrotoxicosis (may be exacerbated by large doses of salicylates)
• Elderly patients are particularly susceptible to the adverse effects of NSAIDs, including acetylsalicylic acid especially gastrointestinal bleeding and perforation which may be fatal (see section …
… sed, unless recommended by a healthcare professional.
Surgical procedures: Acetylsalicylic acid should be stopped several days before scheduled surgical procedures due to increased bleeding time.
Laboratory tests: Acetylsalicylic acid and other salicylates can interfere with thyroid function tests.
Caution should be implemented in patients with a history of other bleeding events such as intracranial haemorrhage, due to the increased risk of intercranial haemorrhage with acetylsalicylic acid us …